Pathogenesis of Schistosoma mansoni infection
نویسندگان
چکیده
منابع مشابه
Immunopathology of Schistosoma mansoni infection.
Schistosomiasis mansoni is a chronic helminthic disease that affects about 100 million people in the tropics. The worms have a life span of 5 to 10 years, and they live in the mesenteric veins of the host. Lightly infected individuals are asymptomatic or manifest mild intestinal symptoms. Heavily infected individuals often develop severe morbidity with hepatosplenomegaly, sometimes with a fatal...
متن کاملImmunodiagnosis of infection with Schistosoma mansoni: Enzyme-
A circulating antigen, a negatively charged polysaccharide from the trematode Schistosoma mansoni, was noncovalently bound to the surface of poly(L-lysine).coated wells in polystyrene trays, which were then used in a micro-enzymelinked immunosorbent assay (ELISA) test. The method provides an immunodiagnostic test for schistosomiasis of exceptional sensitivity with a high degree of specificity. ...
متن کاملExperimental models of Schistosoma mansoni infection.
Experimental models of Schistosoma mansoni infections in mammals have contributed greatly to our understanding of the pathology and pathogenesis of infection. We consider here hepatic and extrahepatic disease in models of acute and chronic infection. Experimental schistosome infections have also contributed more broadly to our understanding of granulomatous inflammation and our understanding of...
متن کاملMetabonomic investigation of human Schistosoma mansoni infection.
Schistosomiasis is a parasitic infection that is endemic in many developing countries in the tropics and subtropics afflicting more than 207 million people primarily in rural areas. After malaria, it is the second most important parasitic infection in terms of socio-economic and public health. Investigation of the host-parasite interaction at the molecular level and identification of biomarkers...
متن کاملCerebral vasculitis associated with Schistosoma mansoni infection
BACKGROUND Cerebral involvement in schistosomiasis is not rare, but it is underdiagnosed because of the lack of clinical suspicion and the frequency of asymptomatic forms. Neurologic complications are generally supported by granuloma formation around ectopic eggs which have migrated to the brain. Moreover, vascular lesions and cerebral arteritis have been well documented in histopathological st...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 1992
ISSN: 0074-0276
DOI: 10.1590/s0074-02761992000800054